PDBe 4g0w

X-ray diffraction
2.7Å resolution

Human topoisomerase iibeta in complex with DNA and ametantrone


Function and Biology Details

Structure analysis Details

Assembly composition:
hetero hexamer (preferred)
Entry contents:
1 distinct polypeptide molecule
2 distinct DNA molecules
Macromolecules (3 distinct):

Ligands and Environments

2 bound ligands:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: NSRRC BEAMLINE BL13B1
Spacegroup: P21
Unit cell:
a: 80.662Å b: 176.424Å c: 93.635Å
α: 90° β: 112.04° γ: 90°
R R work R free
0.168 0.165 0.215