Structure analysis

Carbonic Anhydrase II in complex with N'-sulfamoylpyrrolidine-1-carboximidamide

X-ray diffraction
0.98Å resolution
Source organism: Homo sapiens
Assembly composition:
monomeric (preferred)
Entry contents: 1 distinct polypeptide molecule

Assemblies

Assembly 1 (preferred)
Download    3D Visualisation
Multimeric state: monomeric
Accessible surface area: 11300 Å2
Buried surface area: 1000 Å2
Dissociation area: 100 Å2
Dissociation energy (ΔGdiss): -3 kcal/mol
Dissociation entropy (TΔSdiss): 0 kcal/mol
Interface energy (ΔGint): -38 kcal/mol
Symmetry number: 1

Macromolecules

Chain: A
Length: 260 amino acids
Theoretical weight: 29.29 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P00918 (Residues: 1-260; Coverage: 100%)
Gene name: CA2
Pfam: Eukaryotic-type carbonic anhydrase
InterPro:
CATH: Carbonic Anhydrase II

Search similar proteins