PDBe 4fg9

X-ray diffraction
2.4Å resolution

Crystal structure of human calcium/calmodulin-dependent protein kinase I 1-320 in complex with ATP

Released:

Function and Biology Details

Reaction catalysed:
ATP + a protein = ADP + a phosphoprotein
Biochemical function:
Biological process:
Cellular component:
  • not assigned

Structure analysis Details

Assemblies composition:
monomeric (preferred)
homo hexamer
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Calcium/calmodulin-dependent protein kinase type 1 Chains: A, B
Molecule details ›
Chains: A, B
Length: 320 amino acids
Theoretical weight: 36.42 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q14012 (Residues: 1-320; Coverage: 87%)
Gene name: CAMK1
Sequence domains: Protein kinase domain
Structure domains:

Ligands and Environments

1 bound ligand:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: BSRF BEAMLINE 1W2B
Spacegroup: P63
Unit cell:
a: 83.097Å b: 83.097Å c: 153.004Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.211 0.209 0.249
Expression system: Escherichia coli