PDBe 4f4o

X-ray diffraction
2.9Å resolution

Structure of the Haptoglobin-Haemoglobin Complex

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero hexamer (preferred)
Entry contents:
3 distinct polypeptide molecules
Macromolecules (3 distinct):
Haptoglobin Chains: C, F, I, L
Molecule details ›
Chains: C, F, I, L
Length: 347 amino acids
Theoretical weight: 38.53 KDa
Source organism: Sus scrofa
UniProt:
  • Canonical: Q8SPS7 (Residues: 1-347; Coverage: 100%)
Gene name: HP
Sequence domains: Trypsin
Structure domains:
Hemoglobin subunit beta Chains: B, E, H, K
Molecule details ›
Chains: B, E, H, K
Length: 146 amino acids
Theoretical weight: 16.06 KDa
Source organism: Sus scrofa
UniProt:
  • Canonical: P02067 (Residues: 2-147; Coverage: 99%)
Gene name: HBB
Sequence domains: Globin
Structure domains: Globins
Hemoglobin subunit alpha Chains: A, D, G, J
Molecule details ›
Chains: A, D, G, J
Length: 141 amino acids
Theoretical weight: 15.06 KDa
Source organism: Sus scrofa
UniProt:
  • Canonical: P01965 (Residues: 1-141; Coverage: 100%)
Gene name: HBA
Sequence domains: Globin
Structure domains: Globins

Ligands and Environments


No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SLS BEAMLINE X06SA
Spacegroup: P212121
Unit cell:
a: 72.88Å b: 197.78Å c: 322.07Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.212 0.211 0.228