› 4e9o

X-ray diffraction
1.42Å resolution

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-172965 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Cell surface-binding protein OPG105 Chain: X
Molecule details ›
Chain: X
Length: 269 amino acids
Theoretical weight: 31.32 KDa
Source organism: Vaccinia virus
Expression system: Escherichia coli BL21
UniProt:
  • Canonical: Q1M1K6 (Residues: 1-261; Coverage: 86%)
Gene names: VACAC2_124, VACCL3_124, VAC_DPP17_124, VACli_124, synVACV_124
Sequence domains: Eukaryotic-type carbonic anhydrase
Structure domains: Alpha carbonic anhydrase

Ligands and Environments

1 bound ligand:
Ligand IOD 12 x IOD
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SSRL BEAMLINE BL7-1
Spacegroup: P41
Unit cell:
a: 71.281Å b: 71.281Å c: 44.415Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.174 0.174 0.19
Expression system: Escherichia coli BL21

Quick links

Citations

3 review citations

Discovery of protective B-cell epitopes for development of antimicrobial vaccines and antibody therapeutics.
Sharon et al. (2014)
2 more

14 mentions without citation

Immunogenic proteins and potential delivery platforms for mpox virus vaccine development: A rapid review.
Wang et al. (2023)
13 more