Reviews - 4dom mentioned but not cited (1)
- International Union of Basic and Clinical Pharmacology. XCVI. Pattern recognition receptors in health and disease. Bryant CE, Orr S, Ferguson B, Symmons MF, Boyle JP, Monie TP. Pharmacol Rev 67 462-504 (2015)
Articles - 4dom mentioned but not cited (10)
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- Molecular mechanisms for the subversion of MyD88 signaling by TcpC from virulent uropathogenic Escherichia coli. Snyder GA, Cirl C, Jiang J, Chen K, Waldhuber A, Smith P, Römmler F, Snyder N, Fresquez T, Dürr S, Tjandra N, Miethke T, Xiao TS. Proc Natl Acad Sci U S A 110 6985-6990 (2013)
- Crystal structures of the Toll/Interleukin-1 receptor (TIR) domains from the Brucella protein TcpB and host adaptor TIRAP reveal mechanisms of molecular mimicry. Snyder GA, Deredge D, Waldhuber A, Fresquez T, Wilkins DZ, Smith PT, Durr S, Cirl C, Jiang J, Jennings W, Luchetti T, Snyder N, Sundberg EJ, Wintrode P, Miethke T, Xiao TS. J Biol Chem 289 669-679 (2014)
- Mechanism of bacterial interference with TLR4 signaling by Brucella Toll/interleukin-1 receptor domain-containing protein TcpB. Alaidarous M, Ve T, Casey LW, Valkov E, Ericsson DJ, Ullah MO, Schembri MA, Mansell A, Sweet MJ, Kobe B. J Biol Chem 289 654-668 (2014)
- Conformational dynamics of cancer-associated MyD88-TIR domain mutant L252P (L265P) allosterically tilts the landscape toward homo-dimerization. Zhan C, Qi R, Wei G, Guven-Maiorov E, Nussinov R, Ma B. Protein Eng Des Sel 29 347-354 (2016)
- Pharmacological inhibition of MyD88 homodimerization counteracts renal ischemia reperfusion-induced progressive renal injury in vivo and in vitro. Zhang LM, Liu JH, Xue CB, Li MQ, Xing S, Zhang X, He WT, Jiang FC, Lu X, Zhou P. Sci Rep 6 26954 (2016)
- β-Caryophyllene Ameliorates MSU-Induced Gouty Arthritis and Inflammation Through Inhibiting NLRP3 and NF-κB Signal Pathway: In Silico and In Vivo. Li WY, Yang F, Chen JH, Ren GF. Front Pharmacol 12 651305 (2021)
- Discovery of a Novel MyD88 Inhibitor M20 and Its Protection Against Sepsis-Mediated Acute Lung Injury. Song J, Chen D, Pan Y, Shi X, Liu Q, Lu X, Xu X, Chen G, Cai Y. Front Pharmacol 12 775117 (2021)
- Simultaneous targeting of MyD88 and Nur77 as an effective approach for the treatment of inflammatory diseases. Uzma S, Baig MS. Drug Des Devel Ther 10 1557-1572 (2016)
- Huoxiang Zhengqi Oral Liquid Attenuates LPS-Induced Acute Lung Injury by Modulating Short-Chain Fatty Acid Levels and TLR4/NF-κB p65 Pathway. Tang R, Zhang J, Zhang R, Li X, Lv R, Nan H, Liu J, Zhao Z, He W, Wang L. Biomed Res Int 2023 6183551 (2023)
Reviews citing this publication (9)
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- Type IV secretion system of Brucella spp. and its effectors. Ke Y, Wang Y, Li W, Chen Z. Front Cell Infect Microbiol 5 72 (2015)
- The molecular mechanisms of signaling by cooperative assembly formation in innate immunity pathways. Vajjhala PR, Ve T, Bentham A, Stacey KJ, Kobe B. Mol Immunol 86 23-37 (2017)
- Towards the structure of the TIR-domain signalosome. Nimma S, Ve T, Williams SJ, Kobe B. Curr Opin Struct Biol 43 122-130 (2017)
- Molecular determinants of disease severity in urinary tract infection. Ambite I, Butler D, Wan MLY, Rosenblad T, Tran TH, Chao SM, Svanborg C. Nat Rev Urol 18 468-486 (2021)
- Targeting the TLR signalosome with TIR domain-derived cell-permeable decoy peptides: the current state and perspectives. Toshchakov VY, Javmen A. Innate Immun 26 35-47 (2020)
- Immunomodulation therapy offers new molecular strategies to treat UTI. Butler D, Ambite I, Wan MLY, Tran TH, Wullt B, Svanborg C. Nat Rev Urol 19 419-437 (2022)
- Straightforward Protein-Protein Interaction Interface Mapping via Random Mutagenesis and Mammalian Protein Protein Interaction Trap (MAPPIT). Vyncke L, Masschaele D, Tavernier J, Peelman F. Int J Mol Sci 20 E2058 (2019)
- The WxxxE proteins in microbial pathogenesis. Achi SC, Karimilangi S, Lie D, Sayed IM, Das S. Crit Rev Microbiol 49 197-213 (2023)
Articles citing this publication (38)
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- Inhibition of TLR2 signaling by small molecule inhibitors targeting a pocket within the TLR2 TIR domain. Mistry P, Laird MH, Schwarz RS, Greene S, Dyson T, Snyder GA, Xiao TS, Chauhan J, Fletcher S, Toshchakov VY, MacKerell AD, Vogel SN. Proc Natl Acad Sci U S A 112 5455-5460 (2015)
- Activation of lymphoma-associated MyD88 mutations via allostery-induced TIR-domain oligomerization. Avbelj M, Wolz OO, Fekonja O, Benčina M, Repič M, Mavri J, Krüger J, Schärfe C, Delmiro Garcia M, Panter G, Kohlbacher O, Weber AN, Jerala R. Blood 124 3896-3904 (2014)
- Reconstructing the TIR Side of the Myddosome: a Paradigm for TIR-TIR Interactions. Vyncke L, Bovijn C, Pauwels E, Van Acker T, Ruyssinck E, Burg E, Tavernier J, Peelman F. Structure 24 437-447 (2016)
- Crystal structure of TIR domain of TLR6 reveals novel dimeric interface of TIR-TIR interaction for toll-like receptor signaling pathway. Jang TH, Park HH. J Mol Biol 426 3305-3313 (2014)
- Uropathogenic Escherichia coli strain CFT073 disrupts NLRP3 inflammasome activation. Waldhuber A, Puthia M, Wieser A, Cirl C, Dürr S, Neumann-Pfeifer S, Albrecht S, Römmler F, Müller T, Zheng Y, Schubert S, Groß O, Svanborg C, Miethke T. J Clin Invest 126 2425-2436 (2016)
- Recruitment of TLR adapter TRIF to TLR4 signaling complex is mediated by the second helical region of TRIF TIR domain. Piao W, Ru LW, Piepenbrink KH, Sundberg EJ, Vogel SN, Toshchakov VY. Proc Natl Acad Sci U S A 110 19036-19041 (2013)
- MyD88 TIR domain higher-order assembly interactions revealed by microcrystal electron diffraction and serial femtosecond crystallography. Clabbers MTB, Holmes S, Muusse TW, Vajjhala PR, Thygesen SJ, Malde AK, Hunter DJB, Croll TI, Flueckiger L, Nanson JD, Rahaman MH, Aquila A, Hunter MS, Liang M, Yoon CH, Zhao J, Zatsepin NA, Abbey B, Sierecki E, Gambin Y, Stacey KJ, Darmanin C, Kobe B, Xu H, Ve T. Nat Commun 12 2578 (2021)
- Targeting of MyD88 Homodimerization by Novel Synthetic Inhibitor TJ-M2010-5 in Preventing Colitis-Associated Colorectal Cancer. Xie L, Jiang FC, Zhang LM, He WT, Liu JH, Li MQ, Zhang X, Xing S, Guo H, Zhou P. J Natl Cancer Inst 108 djv364 (2016)
- Discovery of small molecule inhibitors of MyD88-dependent signaling pathways using a computational screen. Olson MA, Lee MS, Kissner TL, Alam S, Waugh DS, Saikh KU. Sci Rep 5 14246 (2015)
- Structure of the Toll/interleukin 1 receptor (TIR) domain of the immunosuppressive Brucella effector BtpA/Btp1/TcpB. Kaplan-Türköz B, Koelblen T, Felix C, Candusso MP, O'Callaghan D, Vergunst AC, Terradot L. FEBS Lett 587 3412-3416 (2013)
- A survey of TIR domain sequence and structure divergence. Toshchakov VY, Neuwald AF. Immunogenetics 72 181-203 (2020)
- Gene structure, cDNA characterization and RNAi-based functional analysis of a myeloid differentiation factor 88 homolog in Tenebrio molitor larvae exposed to Staphylococcus aureus infection. Patnaik BB, Patnaik HH, Seo GW, Jo YH, Lee YS, Lee BL, Han YS. Dev Comp Immunol 46 208-221 (2014)
- TcpC inhibits neutrophil extracellular trap formation by enhancing ubiquitination mediated degradation of peptidylarginine deiminase 4. Ou Q, Fang JQ, Zhang ZS, Chi Z, Fang J, Xu DY, Lu KZ, Qian MQ, Zhang DY, Guo JP, Gao W, Zhang NR, Pan JP. Nat Commun 12 3481 (2021)
- Redox sensitivity of the MyD88 immune signaling adapter. Stottmeier B, Dick TP. Free Radic Biol Med 101 93-101 (2016)
- Short-term Pharmacological Inhibition of MyD88 Homodimerization by a Novel Inhibitor Promotes Robust Allograft Tolerance in Mouse Cardiac and Skin Transplantation. Li C, Zhang LM, Zhang X, Huang X, Liu Y, Li MQ, Xing S, Yang T, Xie L, Jiang FC, Jiang HY, He WT, Zhou P. Transplantation 101 284-293 (2017)
- The Presence of Genotoxic and/or Pro-inflammatory Bacterial Genes in Gut Metagenomic Databases and Their Possible Link With Inflammatory Bowel Diseases. Roche-Lima A, Carrasquillo-Carrión K, Gómez-Moreno R, Cruz JM, Velázquez-Morales DM, Rogozin IB, Baerga-Ortiz A. Front Genet 9 116 (2018)
- A Comparative Analysis of the Mechanism of Toll-Like Receptor-Disruption by TIR-Containing Protein C from Uropathogenic Escherichia coli. Waldhuber A, Snyder GA, Römmler F, Cirl C, Müller T, Xiao TS, Svanborg C, Miethke T. Pathogens 5 E25 (2016)
- Identification of Toll-like receptor signaling inhibitors based on selective activation of hierarchically acting signaling proteins. Ippagunta SK, Pollock JA, Sharma N, Lin W, Chen T, Tawaratsumida K, High AA, Min J, Chen Y, Guy RK, Redecke V, Katzenellenbogen JA, Häcker H. Sci Signal 11 eaaq1077 (2018)
- T3SS-Independent Uptake of the Short-Trip Toxin-Related Recombinant NleC Effector of Enteropathogenic Escherichia coli Leads to NF-κB p65 Cleavage. Stolle AS, Norkowski S, Körner B, Schmitz J, Lüken L, Frankenberg M, Rüter C, Schmidt MA. Front Cell Infect Microbiol 7 119 (2017)
- The TIR Domain Containing Locus of Enterococcus faecalis Is Predominant among Urinary Tract Infection Isolates and Downregulates Host Inflammatory Response. Kraemer TD, Quintanar Haro OD, Domann E, Chakraborty T, Tchatalbachev S. Int J Microbiol 2014 918143 (2014)
- TcpC inhibits toll-like receptor signaling pathway by serving as an E3 ubiquitin ligase that promotes degradation of myeloid differentiation factor 88. Fang JQ, Ou Q, Pan J, Fang J, Zhang DY, Qiu MQ, Li YQ, Wang XH, Yang XY, Chi Z, Gao W, Guo JP, Miethke T, Pan JP. PLoS Pathog 17 e1009481 (2021)
- TcpC secreting uropathogenic E. coli promoted kidney cells to secrete MIP-2 via p38 MAPK pathway. He Y, Fang J, Zhang C, Pan J, Jin Q, Yang Y, Wang L, Wang B, Zhang D, Pan J. Mol Med Rep 16 3528-3534 (2017)
- Dissecting a Hub for Immune Response: Modeling the Structure of MyD88. Naro C, Sette C. Structure 24 349-351 (2016)
- Toll/Interleukin-1 Receptor Domain Derived from TcpC (TIR-TcpC) Ameliorates Experimental Autoimmune Arthritis by Down-modulating Th17 Cell Response. Pasi S, Kant R, Surolia A. J Biol Chem 291 12358-12369 (2016)
- Enterococcus faecium TIR-Domain Genes Are Part of a Gene Cluster Which Promotes Bacterial Survival in Blood. Wagner TM, Janice J, Paganelli FL, Willems RJ, Askarian F, Pedersen T, Top J, de Haas C, van Strijp JA, Johannessen M, Hegstad K. Int J Microbiol 2018 1435820 (2018)
- Blunt Snout Bream (Megalobrama amblycephala) MyD88 and TRAF6: characterisation, comparative homology modelling and expression. Tran NT, Liu H, Jakovlić I, Wang WM. Int J Mol Sci 16 7077-7097 (2015)
- Frontline Science: Targeting the TLR7 signalosome assembly. Javmen A, Szmacinski H, Lakowicz JR, Toshchakov VY. J Leukoc Biol 108 1697-1706 (2020)
- Network Pharmacology- and Molecular Docking-Based Identification of Potential Phytocompounds from Argyreia capitiformis in the Treatment of Inflammation. Obaidullah AJ, Alanazi MM, Alsaif NA, Alanazi AS, Albassam H, Az A, Alwassil OI, Alqahtani AM, Tareq AM. Evid Based Complement Alternat Med 2022 8037488 (2022)
- Recombinant production of functional full-length and truncated human TRAM/TICAM-2 adaptor protein involved in Toll-like receptor and interferon signaling. Ullah MO, Valkov E, Ve T, Williams S, Mas C, Mansell A, Kobe B. Protein Expr Purif 106 31-40 (2015)
- Regulation of Expression of the TIR-Containing Protein C Gene of the Uropathogenic Escherichia coli Strain CFT073. Ittensohn J, Hemberger J, Griffiths H, Keller M, Albrecht S, Miethke T. Pathogens 10 549 (2021)
- The Presence of Gut Microbial Genes Encoding Bacterial Genotoxins or Pro-Inflammatory Factors in Stool Samples from Individuals with Colorectal Neoplasia. Gómez-Moreno R, González-Pons M, Soto-Salgado M, Cruz-Correa M, Baerga-Ortiz A. Diseases 7 E16 (2019)
- Bacterial TIR domain-derived peptides inhibit innate immune signaling and catabolic responses in chondrocyte. Hong L, Wang S, Guo J, Yin X, Yu Q, Yang M, Wang Y, Ke Y, Li W. Mol Biol Rep 46 2493-2504 (2019)
- Cloning, expression, purification, crystallization and preliminary X-ray crystallographic analysis of the TIR domain from the Brucella melitensis TIR-domain-containing protein TcpB. Alaidarous M, Ve T, Ullah MO, Valkov E, Mansell A, Schembri MA, Sweet MJ, Kobe B. Acta Crystallogr Sect F Struct Biol Cryst Commun 69 1167-1170 (2013)
- Human and Bacterial Toll-Interleukin Receptor Domains Exhibit Distinct Dynamic Features and Functions. Lee E, Redzic JS, Nemkov T, Saviola AJ, Dzieciatkowska M, Hansen KC, D'Alessandro A, Dinarello C, Eisenmesser EZ. Molecules 27 4494 (2022)
- Purpurolide C-based microneedle promotes macrophage-mediated diabetic wound healing via inhibiting TLR4-MD2 dimerization and MYD88 phosphorylation. Liu Y, Xia G, Chen Y, Xia H, Xu J, Guo L, Lin S, Liu Y. Acta Pharm Sin B 13 5060-5073 (2023)
- The structure of NAD+ consuming protein Acinetobacter baumannii TIR domain shows unique kinetics and conformations. Klontz E, Obi JO, Wang Y, Glendening G, Carr J, Tsibouris C, Buddula S, Nallar S, Soares AS, Beckett D, Redzic JS, Eisenmesser E, Palm C, Schmidt K, Scudder AH, Obiorah T, Essuman K, Milbrandt J, Diantonio A, Ray K, Snyder MLD, Deredge D, Snyder GA. J Biol Chem 299 105290 (2023)
- [Progress on mechanisms for pathogensto evade NOD-like receptor and Toll-like receptor signaling pathways]. Yujie HE, Jianping P. Zhejiang Da Xue Xue Bao Yi Xue Ban 46 218-224 (2017)