Function and Biology Details
Reaction catalysed:
ATP + 5-amino-1-(5-phospho-D-ribosyl)imidazole + HCO(3)(-) = ADP + phosphate + 5-carboxyamino-1-(5-phospho-D-ribosyl)imidazole
Biochemical function:
Biological process:
Cellular component:
- not assigned
Sequence domains:
- Phosphoribosylaminoimidazole carboxylase, ATPase subunit
- Phosphoribosylaminoimidazole carboxylase, C-terminal domain
- Rudiment single hybrid motif
- ATP-grasp fold, subdomain 1
- ATP-grasp fold, ATP-dependent carboxylate-amine ligase-type
- ATP-grasp fold
- Pre-ATP-grasp domain superfamily
- D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain
Structure analysis Details
Assembly composition:
homo dimer (preferred)
Assembly name:
N5-carboxyaminoimidazole ribonucleotide synthase (preferred)
PDBe Complex ID:
PDB-CPX-105720 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
N5-carboxyaminoimidazole ribonucleotide synthase
Molecule details ›
Chains: A, B
Length: 380 amino acids
Theoretical weight: 42.22 KDa
Source organism: Bacillus anthracis str. A0248
Expression system: Escherichia coli
UniProt:
Sequence domains:
Length: 380 amino acids
Theoretical weight: 42.22 KDa
Source organism: Bacillus anthracis str. A0248
Expression system: Escherichia coli
UniProt:
- Canonical:
A0A6L8P0X7 (Residues: 1-380; Coverage: 99%)
Sequence domains:
- D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain
- ATP-grasp domain
- Phosphoribosylaminoimidazole carboxylase C-terminal domain
