PDBe 4dkc

X-ray diffraction
1.85Å resolution

Crystal Structure of Human Interleukin-34


Function and Biology Details

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Entry contents:
1 distinct polypeptide molecule
Interleukin-34 Chains: A, B
Molecule details ›
Chains: A, B
Length: 190 amino acids
Theoretical weight: 21.86 KDa
Source organism: Homo sapiens
Expression system: Trichoplusia ni
  • Canonical: Q6ZMJ4 (Residues: 21-193; Coverage: 78%)
Gene names: C16orf77, IL34
Sequence domains: Interleukin 34
Structure domains: Growth Hormone; Chain: A;

Ligands and Environments

2 bound ligands:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ALS BEAMLINE 5.0.2
Spacegroup: P21
Unit cell:
a: 57.694Å b: 77.866Å c: 58.083Å
α: 90° β: 103.25° γ: 90°
R R work R free
0.175 0.174 0.203
Expression system: Trichoplusia ni