PDBe 4dgb

X-ray diffraction
1.7Å resolution

TRIMCyp cyclophilin domain from Macaca mulatta: HIV-2 CA cyclophilin-binding loop complex

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Peptidyl-prolyl cis-trans isomerase A Chain: A
Molecule details ›
Chain: A
Length: 165 amino acids
Theoretical weight: 18.02 KDa
Source organism: Macaca mulatta
Expression system: Escherichia coli
UniProt:
  • Canonical: P62940 (Residues: 1-165; Coverage: 100%)
Gene names: CYPA, PPIA
Sequence domains: Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD
Capsid protein p24 Chain: B
Molecule details ›
Chain: B
Length: 6 amino acids
Theoretical weight: 551 Da
Source organism: Human immunodeficiency virus type 2 (ISOLATE ROD)
Expression system: Not provided
UniProt:
  • Canonical: P04590 (Residues: 221-226; Coverage: 1%)
Gene name: gag

Ligands and Environments

No bound ligands

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU RU300
Spacegroup: P212121
Unit cell:
a: 36.17Å b: 55.72Å c: 70.84Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.179 0.178 0.21
Expression systems:
  • Escherichia coli
  • Not provided