PDBe 4daj

X-ray diffraction
3.4Å resolution

Structure of the M3 Muscarinic Acetylcholine Receptor

Released:

Function and Biology Details

Reaction catalysed:
Hydrolysis of (1->4)-beta-linkages between N-acetylmuramic acid and N-acetyl-D-glucosamine residues in a peptidoglycan and between N-acetyl- D-glucosamine residues in chitodextrins. 
Biochemical function:
Biological process:
Cellular component:

Structure analysis Details

Assemblies composition:
monomeric (preferred)
homo dimer
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Muscarinic acetylcholine receptor M3; Endolysin Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 479 amino acids
Theoretical weight: 54.99 KDa
Source organisms: Expression system: Spodoptera frugiperda
UniProt:
  • Canonical: P08483 (Residues: 57-307, 482-589; Coverage: 57%)
  • Canonical: P00720 (Residues: 26-161; Coverage: 83%)
  • nullnull
Gene names: Chrm-3, Chrm3, E
Structure domains:

Ligands and Environments

2 bound ligands:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 23-ID-D
Spacegroup: P1
Unit cell:
a: 54.77Å b: 61.31Å c: 176.91Å
α: 85.87° β: 89.9° γ: 84.9°
R-values:
R R work R free
0.254 0.251 0.303
Expression system: Spodoptera frugiperda