› 4d6b

X-ray diffraction
2.12Å resolution

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-136048 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Myelin P2 protein Chain: A
Molecule details ›
Chain: A
Length: 133 amino acids
Theoretical weight: 14.95 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P02689 (Residues: 1-132; Coverage: 100%)
Gene name: PMP2
Sequence domains: Lipocalin / cytosolic fatty-acid binding protein family
Structure domains: Lipocalin

Ligands and Environments

2 bound ligands:
Ligand SO4 6 x SO4
Ligand PLM 1 x PLM
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: EMBL/DESY, HAMBURG BEAMLINE X12
Spacegroup: P41212
Unit cell:
a: 64.311Å b: 64.311Å c: 101.362Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.221 0.218 0.273
Expression system: Escherichia coli

Quick links

Citations

1 review citation

Sub-Nanosecond Dynamics of Pathologically Relevant Bio-Macromolecules Observed by Incoherent Neutron Scattering.
Matsuo et al. (2022)
6 other articles

2 mentions without citation

Dynamics of the Peripheral Membrane Protein P2 from Human Myelin Measured by Neutron Scattering--A Comparison between Wild-Type Protein and a Hinge Mutant.
Laulumaa et al. (2015)
1 more