PDBe 4coh

X-ray diffraction
2.08Å resolution

Crystal structure of Trypanosoma cruzi CYP51 bound to the sulfonamide derivative of the 4-aminopyridyl-based inhibitor


Function and Biology Details

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule

Ligands and Environments

Cofactor: Ligand HEM 2 x HEM
1 bound ligand:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ALS BEAMLINE 8.3.1
Spacegroup: P212121
Unit cell:
a: 79.218Å b: 96.392Å c: 137.113Å
α: 90° β: 90° γ: 90°
R R work R free
0.178 0.174 0.243