PDBe 4c95

X-ray diffraction
2.69Å resolution

Crystal structure of the carboxy-terminal domain of yeast Ctf4 bound to Sld5

Released:

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
hetero pentamer (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
DNA polymerase alpha-binding protein Chains: A, B, C
Molecule details ›
Chains: A, B, C
Length: 478 amino acids
Theoretical weight: 54.45 KDa
Source organism: Saccharomyces cerevisiae
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q01454 (Residues: 471-927; Coverage: 49%)
Gene names: CHL15, CTF4, P9659.7, POB1, YPR135W
Sequence domains: Minichromosome loss protein, Mcl1, middle region
DNA replication complex GINS protein SLD5 Chains: D, E
Molecule details ›
Chains: D, E
Length: 19 amino acids
Theoretical weight: 2.12 KDa
Source organism: Saccharomyces cerevisiae
Expression system: Not provided
UniProt:
  • Canonical: Q03406 (Residues: 1-19; Coverage: 7%)
Gene names: SLD5, YDR489W

Ligands and Environments

No bound ligands

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: DIAMOND BEAMLINE I04
Unit cell:
a: 88.944Å b: 99.705Å c: 218.577Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.18 0.179 0.214
Expression systems:
  • Escherichia coli BL21(DE3)
  • Not provided