PDBe 4c5l

X-ray diffraction
1.85Å resolution

Structure of the pyridoxal kinase from Staphylococcus aureus in complex with pyridoxal

Released:

Function and Biology Details

Reaction catalysed:
ATP + pyridoxal = ADP + pyridoxal 5'-phosphate. 
Biochemical function:
Biological process:
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Phosphomethylpyrimidine kinase Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 276 amino acids
Theoretical weight: 29.81 KDa
Source organism: Staphylococcus aureus subsp. aureus Mu50
Expression system: Escherichia coli
UniProt:
  • Canonical: A0A0H3JTP0 (Residues: 2-276; Coverage: 100%)
Gene name: SAV0580
Sequence domains: Phosphomethylpyrimidine kinase
Structure domains: UDP-N-acetylmuramoyl-L-alanine:D-glutamate ligase

Ligands and Environments

3 bound ligands:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SLS BEAMLINE X06SA
Spacegroup: P21
Unit cell:
a: 63.44Å b: 102.78Å c: 83.52Å
α: 90° β: 90.44° γ: 90°
R-values:
R R work R free
0.236 0.234 0.275
Expression system: Escherichia coli