Assemblies
Assembly Name:
RNA-directed RNA polymerase NS5
Multimeric state:
hetero dimer
Accessible surface area:
49578.44 Å2
Buried surface area:
3207.22 Å2
Dissociation area:
1,603.61
Å2
Dissociation energy (ΔGdiss):
17.91
kcal/mol
Dissociation entropy (TΔSdiss):
15.29
kcal/mol
Symmetry number:
2
PDBe Complex ID:
PDB-CPX-180558
Macromolecules
Chain: A
Length: 638 amino acids
Theoretical weight: 73.96 KDa
Source organism: Dengue virus
Expression system: Escherichia coli
UniProt:
Pfam:
Length: 638 amino acids
Theoretical weight: 73.96 KDa
Source organism: Dengue virus
Expression system: Escherichia coli
UniProt:
- Canonical:
Q6YMS4 (Residues: 2753-3390; Coverage: 19%)
Pfam:
- Flavivirus RNA-directed RNA polymerase, fingers and palm domains
- Flavivirus RNA-directed RNA polymerase, thumb domain
- RNA-directed RNA polymerase, fingers/palm subdomains, flavivirus
- DNA/RNA polymerase superfamily
- RNA-dependent RNA polymerase, flavivirus
- RNA-directed RNA polymerase, catalytic domain
- RNA-directed RNA polymerase, thumb subdomain, flavivirus
Chain: B
Length: 638 amino acids
Theoretical weight: 73.99 KDa
Source organism: Dengue virus
Expression system: Escherichia coli
UniProt:
Pfam:
Length: 638 amino acids
Theoretical weight: 73.99 KDa
Source organism: Dengue virus
Expression system: Escherichia coli
UniProt:
- Canonical: Q6YMS4 (Residues: 2753-3390; Coverage: 19%)
Pfam:
- Flavivirus RNA-directed RNA polymerase, fingers and palm domains
- Flavivirus RNA-directed RNA polymerase, thumb domain
- RNA-directed RNA polymerase, fingers/palm subdomains, flavivirus
- DNA/RNA polymerase superfamily
- RNA-dependent RNA polymerase, flavivirus
- RNA-directed RNA polymerase, catalytic domain
- RNA-directed RNA polymerase, thumb subdomain, flavivirus
