PDBe 4br0

X-ray diffraction
2.05Å resolution

rat NTPDase2 in complex with Ca AMPNP

Released:

Function and Biology Details

Reaction catalysed:
A nucleoside 5'-triphosphate + 2 H(2)O = a nucleoside 5'-phosphate + 2 phosphate. 
Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Ectonucleoside triphosphate diphosphohydrolase 2 Chain: A
Molecule details ›
Chain: A
Length: 457 amino acids
Theoretical weight: 50.7 KDa
Source organism: Rattus norvegicus
Expression system: Escherichia coli
UniProt:
  • Canonical: O35795 (Residues: 28-462; Coverage: 88%)
Gene names: Cd39l1, Entpd2
Sequence domains: GDA1/CD39 (nucleoside phosphatase) family

Ligands and Environments

3 bound ligands:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: BESSY BEAMLINE 14.2
Spacegroup: P212121
Unit cell:
a: 41.17Å b: 69.13Å c: 164.51Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.171 0.169 0.218
Expression system: Escherichia coli