Function and Biology Details
Biochemical function:
Biological process:
Cellular component:
Sequence domains:
- WD40 repeat
- WD40/YVTN repeat-like-containing domain superfamily
- G-protein beta WD-40 repeat
- WD40 repeat, conserved site
- WD40-repeat-containing domain superfamily
- DNA excision repair protein Rad28/ERCC8/Ckn1/ATCSA-1
- Cleavage/polyadenylation specificity factor, A subunit, C-terminal
- Cleavage/polyadenylation specificity factor, A subunit, N-terminal
Structure analysis Details
Assembly composition:
hetero dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-171603 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
DNA damage-binding protein 1
Molecule details ›
Chain: A
Length: 1159 amino acids
Theoretical weight: 129.39 KDa
Source organism: Homo sapiens
Expression system: Trichoplusia ni
UniProt:
Sequence domains:
Structure domains:
Length: 1159 amino acids
Theoretical weight: 129.39 KDa
Source organism: Homo sapiens
Expression system: Trichoplusia ni
UniProt:
- Canonical:
Q16531 (Residues: 1-1140; Coverage: 100%)
Sequence domains:
Structure domains:
DNA excision repair protein ERCC-8
Molecule details ›
Chain: B
Length: 408 amino acids
Theoretical weight: 45.47 KDa
Source organism: Homo sapiens
Expression system: Trichoplusia ni
UniProt:
Sequence domains: WD domain, G-beta repeat
Structure domains: YVTN repeat-like/Quinoprotein amine dehydrogenase
Length: 408 amino acids
Theoretical weight: 45.47 KDa
Source organism: Homo sapiens
Expression system: Trichoplusia ni
UniProt:
- Canonical: Q13216 (Residues: 1-396; Coverage: 100%)
Sequence domains: WD domain, G-beta repeat
Structure domains: YVTN repeat-like/Quinoprotein amine dehydrogenase
Ligands and Environments
No bound ligands
No modified residues
Experiments and Validation Details
X-ray source:
SLS BEAMLINE X10SA
Spacegroup:
P3221
Expression system: Trichoplusia ni
