PDBe 4a11

X-ray diffraction
3.31Å resolution

Structure of the hsDDB1-hsCSA complex

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
DNA damage-binding protein 1 Chain: A
Molecule details ›
Chain: A
Length: 1159 amino acids
Theoretical weight: 129.39 KDa
Source organism: Homo sapiens
Expression system: Trichoplusia ni
UniProt:
  • Canonical: Q16531 (Residues: 1-1140; Coverage: 100%)
Gene names: DDB1, XAP1
Sequence domains:
Structure domains:
DNA excision repair protein ERCC-8 Chain: B
Molecule details ›
Chain: B
Length: 408 amino acids
Theoretical weight: 45.47 KDa
Source organism: Homo sapiens
Expression system: Trichoplusia ni
UniProt:
  • Canonical: Q13216 (Residues: 1-396; Coverage: 100%)
Gene names: CKN1, CSA, ERCC8
Sequence domains: WD domain, G-beta repeat
Structure domains: YVTN repeat-like/Quinoprotein amine dehydrogenase

Ligands and Environments

No bound ligands

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SLS BEAMLINE X10SA
Spacegroup: P3221
Unit cell:
a: 138.33Å b: 138.33Å c: 244.97Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.178 0.176 0.233
Expression system: Trichoplusia ni