PDBe 4zzi

X-ray diffraction
2.73Å resolution

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
SirtT1 75 kDa fragment Chain: A
Molecule details ›
Chain: A
Length: 356 amino acids
Theoretical weight: 40.13 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q96EB6 (Residues: 183-505; Coverage: 43%)
Gene names: SIR2L1, SIRT1
Sequence domains: Sir2 family
Structure domains:

Ligands and Environments

3 bound ligands:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 21-ID-D
Spacegroup: P6122
Unit cell:
a: 122.15Å b: 122.15Å c: 104.92Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.193 0.191 0.235
Expression system: Escherichia coli