PDBe 4zzh

X-ray diffraction
3.1Å resolution

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
SirtT1 75 kDa fragment Chain: A
Molecule details ›
Chain: A
Length: 356 amino acids
Theoretical weight: 40.13 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q96EB6 (Residues: 183-505; Coverage: 43%)
Gene names: SIR2L1, SIRT1
Sequence domains: Sir2 family

Ligands and Environments

2 bound ligands:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SSRF BEAMLINE BL17U
Spacegroup: I212121
Unit cell:
a: 99.19Å b: 111.64Å c: 132.52Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.189 0.186 0.238
Expression system: Escherichia coli