PDBe 4zrq

X-ray diffraction
2.6Å resolution

E88 deletion mutant of CD320 in complex with TC2

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Transcobalamin-2 Chains: A, B
Molecule details ›
Chains: A, B
Length: 409 amino acids
Theoretical weight: 45.59 KDa
Source organism: Homo sapiens
Expression system: Spodoptera frugiperda
UniProt:
  • Canonical: P20062 (Residues: 19-427; Coverage: 100%)
Gene names: TC2, TCN2
Sequence domains: Domain of unknown function (DUF4430)
Structure domains:
CD320 antigen Chains: C, D
Molecule details ›
Chains: C, D
Length: 118 amino acids
Theoretical weight: 12.66 KDa
Source organism: Homo sapiens
Expression system: Spodoptera frugiperda
UniProt:
  • Canonical: Q9NPF0 (Residues: 53-171; Coverage: 48%)
Gene names: 8D6A, CD320, UNQ198/PRO224
Sequence domains: Low-density lipoprotein receptor domain class A

Ligands and Environments

3 bound ligands:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SLS BEAMLINE X06SA
Spacegroup: P43212
Unit cell:
a: 98.404Å b: 98.404Å c: 356.341Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.2 0.198 0.23
Expression system: Spodoptera frugiperda