PDBe 4y1x

X-ray diffraction
2.45Å resolution

Complex of human Galectin-1 and Galbeta1-4(6OSO3)GlcNAc

Released:
Source organism: Homo sapiens
Entry authors: Lin HY, Hsieh TJ, Lin CH

Function and Biology Details

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Galectin-1 Chains: A, B
Molecule details ›
Chains: A, B
Length: 154 amino acids
Theoretical weight: 16.89 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: NEW P09382 (Residues: 3-135; Coverage: 99%)
Gene name: LGALS1
Sequence domains: Galactoside-binding lectin
Structure domains: Jelly Rolls

Ligands and Environments

2 bound ligands:

1 modified residue:

Experiments and Validation Details

Entry percentile scores
X-ray source: NSRRC BEAMLINE BL13C1
Spacegroup: P212121
Unit cell:
a: 43.579Å b: 57.22Å c: 110.945Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.214 0.21 0.259
Expression system: Escherichia coli BL21(DE3)