PDBe 4xv9

X-ray diffraction
2Å resolution

Function and Biology Details

Reaction catalysed:
ATP + a protein = ADP + a phosphoprotein
Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Serine/threonine-protein kinase B-raf Chain: A
Molecule details ›
Chain: A
Length: 292 amino acids
Theoretical weight: 33.3 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P15056 (Residues: 442-705; Coverage: 35%)
Gene names: BRAF, BRAF1, RAFB1
Structure domains:

Ligands and Environments

2 bound ligands:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SSRL BEAMLINE BL9-1
Spacegroup: P4322
Unit cell:
a: 119.297Å b: 119.297Å c: 52.507Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.206 0.205 0.238
Expression system: Escherichia coli