PDBe 4xh2

X-ray diffraction
2Å resolution

Crystal structure of human paxillin LD4 motif in complex with Fab fragment

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero trimer (preferred)
Entry contents:
3 distinct polypeptide molecules
Macromolecules (3 distinct):
Paxillin Chains: a, c, e, g, h, j
Molecule details ›
Chains: a, c, e, g, h, j
Length: 18 amino acids
Theoretical weight: 1.94 KDa
Source organism: synthetic construct
Expression system: Not provided
UniProt:
  • Canonical: P49023 (Residues: 259-275; Coverage: 3%)
Gene name: PXN
Fab Heavy Chain Chains: A, C, E, G, H, J
Molecule details ›
Chains: A, C, E, G, H, J
Length: 228 amino acids
Theoretical weight: 24.26 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
Fab Light Chain Chains: B, D, F, I, K, L
Molecule details ›
Chains: B, D, F, I, K, L
Length: 217 amino acids
Theoretical weight: 23.71 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli

Ligands and Environments


No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 24-ID-C
Spacegroup: P212121
Unit cell:
a: 117.58Å b: 138.12Å c: 223.51Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.226 0.224 0.258
Expression systems:
  • Not provided
  • Escherichia coli