PDBe 4x34

X-ray diffraction
1.8Å resolution

Crystal structure of the 53BP1 tandem tudor domain in complex with p53K381acK382me2

Released:

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
TP53-binding protein 1 Chains: A, B
Molecule details ›
Chains: A, B
Length: 120 amino acids
Theoretical weight: 13.62 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q12888 (Residues: 1484-1603; Coverage: 6%)
Gene name: TP53BP1
Structure domains:
Cellular tumor antigen p53 Chains: C, D
Molecule details ›
Chains: C, D
Length: 10 amino acids
Theoretical weight: 1.35 KDa
Source organism: Homo sapiens
Expression system: Not provided
UniProt:
  • Canonical: P04637 (Residues: 377-386; Coverage: 3%)
Gene names: P53, TP53

Ligands and Environments

No bound ligands

2 modified residues:

Experiments and Validation Details

Entry percentile scores
X-ray source: ALS BEAMLINE 4.2.2
Spacegroup: C2221
Unit cell:
a: 58.891Å b: 110.939Å c: 96.915Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.188 0.187 0.218
Expression systems:
  • Escherichia coli BL21(DE3)
  • Not provided