PDBe 4wyk

X-ray diffraction
3.4Å resolution

Structure of the LRR and NTF2-like domains of NXF1 complexed with NXT1

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero tetramer (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Nuclear RNA export factor 1 Chains: A, C
Molecule details ›
Chains: A, C
Length: 461 amino acids
Theoretical weight: 52.09 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: NEW Q9UBU9 (Residues: 96-555; Coverage: 74%)
Gene names: NXF1, TAP
Sequence domains:
Structure domains:
NTF2-related export protein 1 Chains: B, D
Molecule details ›
Chains: B, D
Length: 139 amino acids
Theoretical weight: 15.73 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: NEW Q9UKK6 (Residues: 2-140; Coverage: 99%)
Gene name: NXT1
Sequence domains: Nuclear transport factor 2 (NTF2) domain
Structure domains: Nuclear Transport Factor 2; Chain: A,

Ligands and Environments

No bound ligands

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: DIAMOND BEAMLINE I04-1
Spacegroup: P1
Unit cell:
a: 48.046Å b: 83.972Å c: 108.233Å
α: 108.69° β: 99.76° γ: 97.51°
R-values:
R R work R free
0.216 0.213 0.266
Expression system: Escherichia coli