PDBe 4wlf

X-ray diffraction
2.2Å resolution

Crystal structure of L-malate bound MDH2

Source organism: Homo sapiens
Entry authors: Eo YM, Han BG, Ahn HC

Function and Biology Details

Structure analysis Details

Assembly composition:
homo tetramer (preferred)
Entry contents:
1 distinct polypeptide molecule
Malate dehydrogenase, mitochondrial Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 340 amino acids
Theoretical weight: 35.86 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
  • Canonical: P40926 (Residues: 20-338; Coverage: 94%)
Gene name: MDH2
Sequence domains:
Structure domains:

Ligands and Environments

2 bound ligands:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: PAL/PLS BEAMLINE 7A (6B, 6C1)
Spacegroup: P212121
Unit cell:
a: 60.246Å b: 152.183Å c: 155.034Å
α: 90° β: 90° γ: 90°
R R work R free
0.228 0.227 0.247
Expression system: Escherichia coli