PDBe 4um2

X-ray diffraction
2.1Å resolution

Crystal structure of the TPR domain of SMG6

Released:

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Telomerase-binding protein EST1A Chain: A
Molecule details ›
Chain: A
Length: 589 amino acids
Theoretical weight: 67.28 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q86US8 (Residues: 580-1166; Coverage: 41%)
Gene names: C17orf31, EST1A, KIAA0732, SMG6
Sequence domains:

Ligands and Environments

1 bound ligand:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SLS BEAMLINE X10SA
Spacegroup: P212121
Unit cell:
a: 62.08Å b: 80.676Å c: 124.729Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.208 0.206 0.237
Expression system: Escherichia coli BL21(DE3)