PDBe 4u7e

X-ray diffraction
1.6Å resolution

The crystal structure of the complex of LIP5 NTD and IST1 MIM

Released:

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Vacuolar protein sorting-associated protein VTA1 homolog Chain: B
Molecule details ›
Chain: B
Length: 163 amino acids
Theoretical weight: 18.79 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q9NP79 (Residues: 1-162; Coverage: 53%)
Gene names: C6orf55, HSPC228, My012, VTA1
Sequence domains: Vta1 like
Structure domains: Vacuolar protein sorting-associated protein vta1
IST1 homolog Chain: A
Molecule details ›
Chain: A
Length: 25 amino acids
Theoretical weight: 3.01 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P53990 (Residues: 341-364; Coverage: 7%)
Gene names: IST1, KIAA0174

Ligands and Environments

No bound ligands

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 21-ID-F
Spacegroup: P212121
Unit cell:
a: 32.315Å b: 65.578Å c: 78.539Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.179 0.178 0.201
Expression system: Escherichia coli