PDBe 4rqr

X-ray diffraction
1.08Å resolution

Crystal Structure of Human Glutaredoxin with MESNA

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Glutaredoxin-1 Chain: A
Molecule details ›
Chain: A
Length: 109 amino acids
Theoretical weight: 11.94 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21
UniProt:
  • Canonical: P35754 (Residues: 2-106; Coverage: 99%)
Gene names: GLRX, GRX
Sequence domains: Glutaredoxin
Structure domains: Glutaredoxin

Ligands and Environments

1 bound ligand:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ALS BEAMLINE 5.0.2
Spacegroup: C2221
Unit cell:
a: 27.847Å b: 55.414Å c: 130.357Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.173 0.172 0.195
Expression system: Escherichia coli BL21