PDBe 4q27

X-ray diffraction
1.2Å resolution

Galectin-1 in Complex with a Click-Activated N-Acetyllactosamine

Released:
Source organism: Homo sapiens
Entry authors: Grimm C, Bertleff-Zieschang N

Function and Biology Details

Structure analysis Details

Assemblies composition:
homo dimer
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Galectin-1 Chains: A, B
Molecule details ›
Chains: A, B
Length: 136 amino acids
Theoretical weight: 15.02 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P09382 (Residues: 1-135; Coverage: 100%)
Gene name: LGALS1
Sequence domains: Galactoside-binding lectin
Structure domains: Jelly Rolls

Ligands and Environments

2 bound ligands:

1 modified residue:

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE ID23-1
Spacegroup: P212121
Unit cell:
a: 43.468Å b: 58.13Å c: 110.8Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.152 0.151 0.18
Expression system: Escherichia coli