PDBe 4q1p

X-ray diffraction
1.46Å resolution

Galectin-1 in Complex with Ligand NB169

Source organism: Homo sapiens
Entry authors: Grimm C, Bertleff-Zieschang N

Function and Biology Details

Structure analysis Details

Assemblies composition:
homo dimer (preferred)
Entry contents:
1 distinct polypeptide molecule
Galectin-1 Chains: A, B
Molecule details ›
Chains: A, B
Length: 136 amino acids
Theoretical weight: 15.02 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
  • Canonical: NEW P09382 (Residues: 1-135; Coverage: 100%)
Gene name: LGALS1
Sequence domains: Galactoside-binding lectin
Structure domains: Jelly Rolls

Ligands and Environments

3 bound ligands:

1 modified residue:

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE ID23-1
Spacegroup: P212121
Unit cell:
a: 43.267Å b: 58.373Å c: 111.066Å
α: 90° β: 90° γ: 90°
R R work R free
0.151 0.149 0.188
Expression system: Escherichia coli