PDBe 4pyp

X-ray diffraction
3.17Å resolution

Crystal structure of the human glucose transporter GLUT1

Released:
Source organism: Homo sapiens
Primary publication:
Crystal structure of the human glucose transporter GLUT1.
Nature 510 121-5 (2014)
PMID: 24847886

Function and Biology Details

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Solute carrier family 2, facilitated glucose transporter member 1 Chain: A
Molecule details ›
Chain: A
Length: 504 amino acids
Theoretical weight: 55.74 KDa
Source organism: Homo sapiens
Expression system: Trichoplusia ni
UniProt:
  • Canonical: P11166 (Residues: 1-492; Coverage: 100%)
Gene names: GLUT1, SLC2A1
Sequence domains: Sugar (and other) transporter
Structure domains: MFS general substrate transporter like domains

Ligands and Environments

1 bound ligand:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SSRF BEAMLINE BL17U
Spacegroup: C2
Unit cell:
a: 120.509Å b: 101.996Å c: 65.604Å
α: 90° β: 101.27° γ: 90°
R-values:
R R work R free
0.234 0.232 0.278
Expression system: Trichoplusia ni