PDBe 4pol

X-ray diffraction
2.8Å resolution

Crystal structures of thioredoxin with mesna at 2.8A resolution


Function and Biology Details

Structure analysis Details

Assemblies composition:
monomeric (preferred)
homo tetramer
Entry contents:
1 distinct polypeptide molecule
Thioredoxin Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 109 amino acids
Theoretical weight: 12.05 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
  • Canonical: P10599 (Residues: 1-105; Coverage: 100%)
Gene names: TRDX, TRX, TRX1, TXN
Sequence domains: Thioredoxin
Structure domains: Glutaredoxin

Ligands and Environments

1 bound ligand:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ALS BEAMLINE 5.0.1
Spacegroup: C2
Unit cell:
a: 85.478Å b: 57.923Å c: 94.902Å
α: 90° β: 90.34° γ: 90°
R R work R free
0.248 0.245 0.312
Expression system: Escherichia coli