PDBe 4p57

X-ray diffraction
2.6Å resolution

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
HLA class II histocompatibility antigen, DP alpha 1 chain Chains: A, C
Molecule details ›
Chains: A, C
Length: 183 amino acids
Theoretical weight: 21.17 KDa
Source organism: Homo sapiens
Expression system: unidentified baculovirus
UniProt:
  • Canonical: P20036 (Residues: 32-214; Coverage: 79%)
Gene names: HLA-DP1A, HLA-DPA1, HLASB
Sequence domains:
Structure domains:
HLA class II histocompatibility antigen, DP beta 1 chain Chains: B, D
Molecule details ›
Chains: B, D
Length: 212 amino acids
Theoretical weight: 24.39 KDa
Source organism: Homo sapiens
Expression system: unidentified baculovirus
UniProt:
  • Canonical: P04440 (Residues: 16-17, 32-218; Coverage: 76%)
Gene names: HLA-DP1B, HLA-DPB1
Sequence domains:
Structure domains:

Ligands and Environments

3 bound ligands:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 24-ID-C
Spacegroup: P41212
Unit cell:
a: 102.392Å b: 102.392Å c: 234.33Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.21 0.208 0.245
Expression system: unidentified baculovirus