PDBe 4oo4

X-ray diffraction
0.97Å resolution

Crystal Structure of Human Thioredoxin Mutant

Released:
Source organism: Homo sapiens
Entry authors: The J, Weichsel A, Montfort WR

Function and Biology Details

Structure analysis Details

Assemblies composition:
monomeric (preferred)
homo dimer
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Thioredoxin Chains: A, B
Molecule details ›
Chains: A, B
Length: 105 amino acids
Theoretical weight: 11.66 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: P10599 (Residues: 1-105; Coverage: 100%)
Gene names: TRDX, TRX, TRX1, TXN
Sequence domains: Thioredoxin
Structure domains: Glutaredoxin

Ligands and Environments

No bound ligands

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SSRL BEAMLINE BL9-2
Spacegroup: P21
Unit cell:
a: 35.269Å b: 50.182Å c: 51.066Å
α: 90° β: 94.08° γ: 90°
R-values:
R R work R free
0.137 0.136 0.165
Expression system: Escherichia coli BL21(DE3)