PDBe 4om7

X-ray diffraction
2.2Å resolution

Crystal structure of TIR domain of TLR6


Function and Biology Details

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Entry contents:
1 distinct polypeptide molecule
Toll-like receptor 6 Chains: A, B
Molecule details ›
Chains: A, B
Length: 179 amino acids
Theoretical weight: 21.21 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
  • Canonical: NEW Q9Y2C9 (Residues: 640-796; Coverage: 21%)
Gene name: TLR6
Sequence domains: TIR domain
Structure domains: Toll/interleukin-1 receptor homology (TIR) domain

Ligands and Environments

No bound ligands

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: PAL/PLS BEAMLINE 5C (4A)
Spacegroup: C2
Unit cell:
a: 127.607Å b: 44.199Å c: 75.723Å
α: 90° β: 118.9° γ: 90°
R R work R free
0.236 0.233 0.285
Expression system: Escherichia coli