PDBe 4nt6

X-ray diffraction
1.84Å resolution

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero trimer (preferred)
Entry contents:
3 distinct polypeptide molecules
Macromolecules (3 distinct):
HLA class I histocompatibility antigen, Cw-8 alpha chain Chain: A
Molecule details ›
Chain: A
Length: 274 amino acids
Theoretical weight: 31.77 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P30505 (Residues: 26-298; Coverage: 80%)
Gene names: HLA-C, HLAC
Sequence domains: Immunoglobulin C1-set domain
Structure domains:
Beta-2-microglobulin Chain: B
Molecule details ›
Chain: B
Length: 99 amino acids
Theoretical weight: 11.75 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P61769 (Residues: 21-118; Coverage: 99%)
Gene names: B2M, CDABP0092, HDCMA22P
Sequence domains: Immunoglobulin C1-set domain
Structure domains: Immunoglobulins
Matrix protein 1 Chain: C
Molecule details ›
Chain: C
Length: 9 amino acids
Theoretical weight: 966 Da
Source organism: Influenza A virus (A/Boston/115JC/2009(H1N1))
Expression system: Not provided
UniProt:
  • Canonical: D9J353 (Residues: 2-10; Coverage: 50%)
Gene name: M1

Ligands and Environments

No bound ligands

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: BRUKER AXS MICROSTAR
Spacegroup: C2
Unit cell:
a: 94.401Å b: 75.687Å c: 61.88Å
α: 90° β: 120.29° γ: 90°
R-values:
R R work R free
0.183 0.18 0.229
Expression systems:
  • Escherichia coli
  • Not provided