PDBe 4np8

X-ray diffraction
1.51Å resolution

Structure of an amyloid forming peptide VQIVYK from the second repeat region of tau (alternate polymorph)

Released:
Source organism: Homo sapiens

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
homo octamer (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Microtubule-associated protein tau Chain: A
Molecule details ›
Chain: A
Length: 6 amino acids
Theoretical weight: 750 Da
Source organism: Homo sapiens
Expression system: Not provided
UniProt:
  • Canonical: P10636 (Residues: 623-628; Coverage: 1%)
Gene names: MAPT, MAPTL, MTBT1, TAU

Ligands and Environments

No bound ligands

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 24-ID-E
Spacegroup: C2
Unit cell:
a: 28.635Å b: 4.88Å c: 35.807Å
α: 90° β: 110.47° γ: 90°
R-values:
R R work R free
0.179 0.177 0.196
Expression system: Not provided