PDBe 4mkt

X-ray diffraction
1.62Å resolution

Human Leukotriene A4 Hydrolase in complex with Pro-Gly-Pro analogue and 4-(4-benzylphenyl)thiazol-2-amine

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Leukotriene A-4 hydrolase Chain: A
Molecule details ›
Chain: A
Length: 611 amino acids
Theoretical weight: 69.36 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P09960 (Residues: 1-611; Coverage: 100%)
Gene names: LTA4, LTA4H
Sequence domains:
Structure domains:

Ligands and Environments


No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: BESSY BEAMLINE 14.1
Spacegroup: P212121
Unit cell:
a: 76.809Å b: 87.588Å c: 100.056Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.158 0.156 0.193
Expression system: Escherichia coli