PDBe 4lnp

X-ray diffraction
1.41Å resolution

The first SH3 domain from CAP/Ponsin in complex with proline rich peptide from Vinculin

Released:

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Sorbin and SH3 domain-containing protein 1 Chain: A
Molecule details ›
Chain: A
Length: 61 amino acids
Theoretical weight: 7.26 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q9BX66 (Residues: 794-854; Coverage: 5%)
Gene names: KIAA0894, KIAA1296, SH3D5, SORBS1
Sequence domains: Variant SH3 domain
Structure domains: SH3 Domains
Vinculin Chain: B
Molecule details ›
Chain: B
Length: 10 amino acids
Theoretical weight: 1.08 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P18206 (Residues: 870-879; Coverage: 1%)
Gene name: VCL

Ligands and Environments

No bound ligands

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SSRF BEAMLINE BL17U
Spacegroup: P212121
Unit cell:
a: 24.48Å b: 49.85Å c: 58.94Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.14 0.137 0.194
Expression system: Escherichia coli