PDBe 4lg6

X-ray diffraction
1.8Å resolution

Crystal structure of ANKRA2-CCDC8 complex

Released:

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Ankyrin repeat family A protein 2 Chain: A
Molecule details ›
Chain: A
Length: 173 amino acids
Theoretical weight: 18.78 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21
UniProt:
  • Canonical: Q9H9E1 (Residues: 142-313; Coverage: 55%)
Gene names: ANKRA, ANKRA2
Sequence domains:
Structure domains: Ankyrin repeat-containing domain
Coiled-coil domain-containing protein 8 Chain: B
Molecule details ›
Chain: B
Length: 17 amino acids
Theoretical weight: 2.08 KDa
Source organism: Homo sapiens
Expression system: Not provided
UniProt:
  • Canonical: Q9H0W5 (Residues: 494-510; Coverage: 3%)
Gene name: CCDC8

Ligands and Environments

1 bound ligand:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: Rigaku FR-E
Spacegroup: P21
Unit cell:
a: 38.726Å b: 49.791Å c: 41.243Å
α: 90° β: 98.23° γ: 90°
R-values:
R R work R free
0.197 0.196 0.208
Expression systems:
  • Escherichia coli BL21
  • Not provided