PDBe 4kke

X-ray diffraction
2.2Å resolution

The crystal structure of AMP-bound JNK3

Released:
Source organism: Homo sapiens
Entry authors: Han BG, Shim MB, Ahn HC

Function and Biology Details

Reaction catalysed:
ATP + a protein = ADP + a phosphoprotein
Biochemical function:
Biological process:
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Mitogen-activated protein kinase 10 Chain: A
Molecule details ›
Chain: A
Length: 365 amino acids
Theoretical weight: 42.12 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: NEW P53779 (Residues: 40-402; Coverage: 78%)
Gene names: JNK3, JNK3A, MAPK10, PRKM10, SAPK1B
Sequence domains: Protein kinase domain
Structure domains:

Ligands and Environments

1 bound ligand:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: PAL/PLS BEAMLINE 5C (4A)
Spacegroup: P212121
Unit cell:
a: 51.979Å b: 71.311Å c: 107.631Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.233 0.23 0.291
Expression system: Escherichia coli