PDBe 4jqx

X-ray diffraction
1.9Å resolution

HLA-B*44:03 in complex with Epstein-Barr virus BZLF1-derived peptide (residues 169-180)

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero trimer (preferred)
Entry contents:
3 distinct polypeptide molecules
Macromolecules (3 distinct):
HLA class I histocompatibility antigen, B-44 alpha chain Chain: A
Molecule details ›
Chain: A
Length: 278 amino acids
Theoretical weight: 32.15 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P30481 (Residues: 25-302; Coverage: 82%)
Gene names: HLA-B, HLAB
Sequence domains:
Structure domains:
Beta-2-microglobulin Chain: C
Molecule details ›
Chain: C
Length: 99 amino acids
Theoretical weight: 11.75 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P61769 (Residues: 21-119; Coverage: 100%)
Gene names: B2M, CDABP0092, HDCMA22P
Sequence domains: Immunoglobulin C1-set domain
Structure domains: Immunoglobulins
Trans-activator protein BZLF1 Chain: B
Molecule details ›
Chain: B
Length: 12 amino acids
Theoretical weight: 1.52 KDa
Source organism: Human gammaherpesvirus 4
Expression system: Not provided
UniProt:
  • Canonical: Q3KSS8 (Residues: 169-180; Coverage: 5%)
Gene name: BZLF1

Ligands and Environments

2 bound ligands:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: AUSTRALIAN SYNCHROTRON BEAMLINE MX1
Spacegroup: P212121
Unit cell:
a: 50.816Å b: 81.619Å c: 110.336Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.196 0.195 0.231
Expression systems:
  • Escherichia coli
  • Not provided