› 4jq5

X-ray diffraction
2.2Å resolution

Crystal structure of the human Nup49CCS2+3* coiled-coil segment

Released:
DOI: 10.2210/pdb4jq5/pdb
PDB entry 4jq5 coloured by chain, front view.
PDB entry 4jq5 coloured by chain, side view.
PDB entry 4jq5 coloured by chain, top view.
Source organism: Homo sapiens
Primary publication:
Architecture of the fungal nuclear pore inner ring complex.
Stuwe T, Bley CJ, Thierbach K, Petrovic S, Schilbach S, Mayo DJ, Perriches T, Rundlet EJ, Jeon YE, Collins LN, Huber FM, Lin DH, Paduch M, Koide A, Lu V, Fischer J, Hurt E, Koide S, Kossiakoff AA, Hoelz A
Science 350 56-64 (2015)
PMID: 26316600

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domain:

Structure analysis Details

Assembly composition:
homo tetramer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-189763 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Nucleoporin p58/p45 Chains: A, B, C, D, E, F, G, H, I, J, K, L
Molecule details ›
Chains: A, B, C, D, E, F, G, H, I, J, K, L
Length: 86 amino acids
Theoretical weight: 10.14 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q9BVL2 (Residues: 341-425; Coverage: 14%)
Gene names: KIAA0410, NUP58, NUPL1
Structure domains: Helix Hairpins

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ALS BEAMLINE 8.2.1
Spacegroup: P1
Unit cell:
a: 63.82Å b: 77.097Å c: 77.197Å
α: 120.04° β: 90.12° γ: 89.96°
R-values:
R R work R free
0.285 0.285 0.293
Expression system: Escherichia coli

Quick links

Citations

22 review citations

The nuclear pore complex: understanding its function through structural insight.
Beck et al. (2017)
21 more

1 mention without citation

Architecture of the fungal nuclear pore inner ring complex.
Stuwe et al. (2015)