PDBe 4jmh

X-ray diffraction
2.41Å resolution

Crystal structure of synthetic protein in complex with double pY peptide

Released:

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Clamp Shc1_pY239/240 Chain: A
Molecule details ›
Chain: A
Length: 202 amino acids
Theoretical weight: 22.33 KDa
Source organism: synthetic construct
Expression system: Escherichia coli
SHC-transforming protein 1 Chain: B
Molecule details ›
Chain: B
Length: 13 amino acids
Theoretical weight: 1.74 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P29353 (Residues: 344-356; Coverage: 2%)
Gene names: SHC, SHC1, SHCA

Ligands and Environments

No bound ligands

1 modified residue:

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 23-ID-B
Spacegroup: C2221
Unit cell:
a: 89.853Å b: 92.19Å c: 59.596Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.216 0.213 0.276
Expression system: Escherichia coli