PDBe 4ima

X-ray diffraction
1.95Å resolution

The structure of C436M-hLPYK in complex with Citrate/Mn/ATP/Fru-1,6-BP

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
homo tetramer (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Pyruvate kinase PKLR Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 543 amino acids
Theoretical weight: 58.57 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P30613 (Residues: 34-574; Coverage: 94%)
  • Best match: P30613-2 (Residues: 1-543)
Gene names: PK1, PKL, PKLR
Sequence domains:
Structure domains:

Ligands and Environments


No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 19-ID
Spacegroup: P21
Unit cell:
a: 82.751Å b: 204.727Å c: 86.532Å
α: 90° β: 96.75° γ: 90°
R-values:
R R work R free
0.2 0.198 0.233
Expression system: Escherichia coli