PDBe 4ig7

X-ray diffraction
2Å resolution

Crystal structure of Trichinella spiralis UCH37 bound to Ubiquitin vinyl methyl ester


Function and Biology Details

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Putative ubiquitin carboxyl-hydrolase ubh-4 Chain: A
Molecule details ›
Chain: A
Length: 343 amino acids
Theoretical weight: 38.81 KDa
Source organism: Trichinella spiralis
Expression system: Escherichia coli
  • Canonical: E5S6X1 (Residues: 634-640, 641-793, 794-882; Coverage: 28%)
Gene name: Tsp_07066
Sequence domains: Ubiquitin carboxyl-terminal hydrolases
Structure domains: Peptidase C12, ubiquitin carboxyl-terminal hydrolase
Ubiquitin Chain: B
Molecule details ›
Chain: B
Length: 75 amino acids
Theoretical weight: 8.52 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
  • Canonical: P0CG48 (Residues: 609-683; Coverage: 11%)
Gene name: UBC
Sequence domains: Ubiquitin family
Structure domains: Phosphatidylinositol 3-kinase Catalytic Subunit; Chain A, domain 1

Ligands and Environments

1 bound ligand:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 23-ID-B
Spacegroup: R3
Unit cell:
a: 147.361Å b: 147.361Å c: 40.485Å
α: 90° β: 90° γ: 120°
R R work R free
0.195 0.193 0.24
Expression system: Escherichia coli