PDBe 4gvd

X-ray diffraction
1.85Å resolution

Crystal Structure of T-cell Lymphoma Invasion and Metastasis-1 PDZ in complex with Syndecan1 Peptide


Function and Biology Details

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
T-lymphoma invasion and metastasis-inducing protein 1 Chains: A, B
Molecule details ›
Chains: A, B
Length: 94 amino acids
Theoretical weight: 10.15 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
  • Canonical: Q13009 (Residues: 841-930; Coverage: 6%)
Gene name: TIAM1
Sequence domains: PDZ domain
Structure domains: Pdz3 Domain
Syndecan-1 Chains: C, D
Molecule details ›
Chains: C, D
Length: 8 amino acids
Theoretical weight: 1.02 KDa
Source organism: Homo sapiens
Expression system: Not provided
  • Canonical: P18827 (Residues: 303-310; Coverage: 3%)
Gene names: SDC, SDC1

Ligands and Environments

3 bound ligands:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ALS BEAMLINE 4.2.2
Spacegroup: P21
Unit cell:
a: 26.517Å b: 58.106Å c: 50.948Å
α: 90° β: 90.5° γ: 90°
R R work R free
0.198 0.196 0.243
Expression systems:
  • Escherichia coli BL21(DE3)
  • Not provided