PDBe 4g0d

X-ray diffraction
2.54Å resolution

Human collagenase 3 (MMP-13) full form with peptides from pro-domain

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Collagenase 3 Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 368 amino acids
Theoretical weight: 42.28 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P45452 (Residues: 104-471; Coverage: 81%)
Gene name: MMP13
Sequence domains:
Structure domains:
Collagenase 3 Chains: W, X, Y, Z
Molecule details ›
Chains: W, X, Y, Z
Length: 26 amino acids
Theoretical weight: 3.11 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P45452 (Residues: 25-50; Coverage: 6%)
Gene name: MMP13

Ligands and Environments


No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE ID23-2
Spacegroup: P21
Unit cell:
a: 101.26Å b: 105.9Å c: 101.18Å
α: 90° β: 102.11° γ: 90°
R-values:
R R work R free
0.172 0.169 0.241
Expression system: Escherichia coli