PDBe 4fzd

X-ray diffraction
3.25Å resolution

Crystal structure of MST4-MO25 complex with WSF motif

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero trimer (preferred)
Entry contents:
3 distinct polypeptide molecules
Macromolecules (3 distinct):
Calcium-binding protein 39 Chain: A
Molecule details ›
Chain: A
Length: 328 amino acids
Theoretical weight: 38.31 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: NEW Q9Y376 (Residues: 11-334; Coverage: 95%)
Gene names: CAB39, CGI-66, MO25
Structure domains: Leucine-rich Repeat Variant
Serine/threonine-protein kinase 26 Chain: B
Molecule details ›
Chain: B
Length: 283 amino acids
Theoretical weight: 31.93 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: NEW Q9P289 (Residues: 18-297; Coverage: 67%)
Gene names: MASK, MST4, STK26
Sequence domains: Protein kinase domain
Structure domains:
Serine/threonine-protein kinase 26 Chain: C
Molecule details ›
Chain: C
Length: 5 amino acids
Theoretical weight: 669 Da
Source organism: Homo sapiens
Expression system: Not provided
UniProt:
  • Canonical: NEW Q9P289 (Residues: 323-327; Coverage: 1%)
Gene names: MASK, MST4, STK26

Ligands and Environments

1 bound ligand:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SSRF BEAMLINE BL17U
Spacegroup: I432
Unit cell:
a: 239.259Å b: 239.259Å c: 239.259Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.222 0.22 0.26
Expression systems:
  • Escherichia coli
  • Not provided